45 Culture of responsive and flexible manufacturing in the shop-floor. Our operational excellence framework has the Shop-floor Transformation Initiative (SFTI) at the core, which empowers the shop-floor team members and emphasizes the continuous development of manufacturing facilities and techniques along the dimensions of people, assets, and process, to demonstrate our flexibility and responsiveness to the customers and prepare us for the future. We have sustained improvement in PQCDSM (Productivity, Quality, Cost, Delivery, Safety, and Morale achieved through continuous recognition practice) through this initiative. Implementing 5S at the shop-floor, monitoring and correcting abnormalities, unsafe conditions/acts, making cGMP observations, recording Batch cycle time (BCT), and Batch charge frequency (BCF), critical for productivity enhancement, manufacturing is building a culture of responsiveness. SFTI has made shop-floor communication regular, focusing on immediate problem solving, providing a platform for setting productivity expectations while keeping our operations audit-ready, contributing to manufacturing capability and process innovation. In the CDMO space, supply partners who can anticipate future needs, combined with a willingness to make adaptable, customized support available are preferred. Suitable to sustaining as a partner of choice, we undertook 10% of the total projects as proactive ones in 2019 – 2020, which secure the supply chain, mitigate the risks for the customer while allowing us to improve the process by optimizing cost and improving environmental efficiencies. Ownership SFTI helps organization to align People, Processes and Assets to business strategy resulting in better Reliability, Quality and Effectiveness as expected by customer. Efficiency Execution Process People Asset Strategy Making complex development possible In a project for the supply of NCE for Phase 1 studies, we integrated our chemistry skills to develop a 21 stages synthesis. A product requiring three intermediates, we developed the technical package from scratch and paved the way for timely and effective technology transfer. We successfully navigated from feasibility through development and optimization, with a simplified approach eliminating column purification and carried out plant scale-up within six months from the start.
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