By visiting our website or using services provided by Sai Life Sciences, you are accepting the practices described in the Privacy Policy.

We also use cookies on our websites. Cookies allow us to give you the best browsing experience and help us to understand how you use our site. You can disable cookies but parts of our website may not work. By continuing to use this website, you agree that we may store and access cookies on your device.

By clicking “I Accept”, you confirm that you are above the age of 16, that you have read and understood the Cookies Usage and the Privacy Policy, and that you agree to the collection, use and processing of your Personal Information by Sai Life in accordance with said policies.

I accept

Stay up to date with our newsletter

Get in touch!

To explore career opportunities with Sai Life Sciences, share your CV here.

Lets start the conversation!

Sign up to our newsletter

Thank you!
We will be in touch shortly.

Biology Facility, Hyderabad, India

The new state-of-the-art Biology facility, located at Sai Life Sciences’ Integrated R&D campus in Hyderabad, houses a comprehensive suite of in vitro and in vivo biology services, DMPK, toxicology and a vivarium.

Discovery biology facility
Biology Block Highlights

We provide differentiated value to our discovery clients through an integrated delivery model across Boston and Hyderabad. By bringing the best of talent, technology, complementary services and efficiency, we deliver unique value to our clients and undertake integrated discovery mandates at scale.

Services

In Vitro

  • Fit-for-purpose assay development
  • Integrated projects with chemistry, DMPK and Tox
  • Throughput screening & SAR support
  • Cell line generation
  • Cell assays & High content screening
  • Protein production
  • Biochemical assays
  • SPR

In Vivo

  • Target engagement/PK-PD studies
  • Biomarker assessments
  • Efficacy models

DMPK

  • In vitro ADME
  • In vivo evaluation in rodents and dogs
  • Bioanalysis and biotransformation/ metabolite identification

Toxicology

  • Customized toxicology studies
  • Acute Toxicity Studies (Rodents and Non-Rodents)
  • Toxicokinetics study in Rodents (Rats or Mice) and non-Rodents (Dogs)

Instruments & Capabilities

  • Liquid handlers (Echo650 & Tecan)
  • Reagent dispensers (Multidrop & VIAFLO)
  • Plate washers with stackers
  • Multimode plate readers (Envision, Tecan and Flexstation III)
  • High Content Imagers Operetta CLS
  • Flow cytometers
  • FLIPR
  • EVOS FL auto imaging system
  • Tissue-lyser
  • AKTA prime plus (protein production)
  • Patch-clamp (Manual)
  • MicroBeta2 & Cell harvester (for radio-ligand assays)
  • Powerlab (Cardiovascular)
  • Compound Management

Expertise

Diverse Targets

  • GPCRs
  • Ion channels
  • Enzymes
  • Epigenetic targets
  • Nuclear Hormone Receptors
  • Pattern recognition receptors etc.

Varied Technologies

  • HTRF, TR-FRET, LanthaScreen, AlphaLISA,
  • Fluorescence polarization
  • ELISA; Luminex
  • Luminescence, ADP Glo, Kinase Glo
  • NanoBRET cell assays
  • Reporter assays
  • Flow cytometry, Immune cell phenotyping
  • IF & high content imaging
  • SPR
  • PCR, RT/qPCR
  • CRISPR
From Discovery to CMC: Outsourcing via integrated partnerships simplifies the externalization journey

To know more about how we can accelerate your drug discovery program, do get in touch!