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Biology Facility, Hyderabad, India

The new state-of-the-art Biology facility, located at Sai Life Sciences’ Integrated R&D campus in Hyderabad, houses a comprehensive suite of in vitro and in vivo biology services, DMPK, toxicology and a vivarium.

Biology facility, Hyderabad
Biology facility highlights

We provide differentiated value to our discovery clients through an integrated delivery model across Boston and Hyderabad. By bringing the best of talent, technology, complementary services and efficiency, we deliver unique value to our clients and undertake integrated discovery mandates at scale.

Services

In Vitro

  • Fit-for-purpose assay development
  • Integrated projects with chemistry, DMPK and Tox
  • Throughput screening & SAR support
  • Cell line generation
  • Cell assays & High content screening
  • Protein production
  • Biochemical assays
  • SPR

In Vivo

  • Target engagement/PK-PD studies
  • Biomarker assessments
  • Efficacy models

DMPK

  • In vitro ADME
  • In vivo evaluation in rodents and dogs
  • Bioanalysis and biotransformation/ metabolite identification

Toxicology

  • Customized toxicology studies
  • Acute Toxicity Studies (Rodents and Non-Rodents)
  • Toxicokinetics study in Rodents (Rats or Mice) and non-Rodents (Dogs)
Biology services
Biology services
Biology services
Biology services
Biology facility: Instruments & Capabilities
Biology facility: Instruments & Capabilities
Biology facility: Instruments & Capabilities
Biology facility: Instruments & Capabilities
Biology facility: Instruments & Capabilities

Instruments & Capabilities

  • Liquid handlers (Echo650 & Tecan)
  • Reagent dispensers (Multidrop & VIAFLO)
  • Plate washers with stackers
  • Multimode plate readers (Envision, Tecan and Flexstation III)
  • High Content Imagers Operetta CLS
  • Flow cytometers
  • FLIPR
  • EVOS FL auto imaging system
  • Tissue-lyser
  • AKTA prime plus (protein production)
  • Patch-clamp (Manual)
  • MicroBeta2 & Cell harvester (for radio-ligand assays)
  • Powerlab (Cardiovascular)
  • Compound Management

Expertise

Diverse Targets

  • GPCRs
  • Ion channels
  • Enzymes
  • Epigenetic targets
  • Nuclear Hormone Receptors
  • Pattern recognition receptors etc.

Varied Technologies

  • HTRF, TR-FRET, LanthaScreen, AlphaLISA,
  • Fluorescence polarization
  • ELISA; Luminex
  • Luminescence, ADP Glo, Kinase Glo
  • NanoBRET cell assays
  • Reporter assays
  • Flow cytometry, Immune cell phenotyping
  • IF & high content imaging
  • SPR
  • PCR, RT/qPCR
  • CRISPR
Discovery biology services & solutions
Discovery biology services & solutions
Discovery biology services & solutions
Discovery biology services & solutions
Discovery biology services & solutions

To know more about how we can accelerate your drug discovery program, do get in touch!

 

Discovery Biology Laboratory in Boston, MA, USA

Discovery Biology Lab, Boston, USA

Located in the heart of the Cambridge-Boston biotech ecosystem, this 8,500 Sq. ft. discovery biology facility provides exploratory biology services to the expanding array of start-up and biotech companies in the Boston area and to companies in North America. It enables opportunities for companies to have face-to-face collaborations with Sai scientists, and to accelerate the pace of their externalized research by reducing cycle times.
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