Our R&D and manufacturing facilities are built to global standards and cater to an international set of clients. Several new facilities are planned for the near future and existing ones are expanding with state-of-the-art blocks. Our headquarters are in Hyderabad, right in the middle of India. We pride ourselves in a global reach.
Discovery R&D centre
Our discovery centre in Pune helps innovator companies accelerate their drug discovery journey from HIT to IND. This 100,000 sq. ft. lab space accommodates 16 chemistry labs with 110 fume hoods, 3 MedChem analytical labs, DMPK/Tox labs including vivarium, Biology with Xenograft facility and Formulation labs. The site includes a cytotoxic formulation lab to handle OEL 4 compounds.
Our flagship R&D centre in Hyderabad, India delivers projects involving complex chemical synthesis from route scouting, process development, scale-up to commercial scale. Staffed with 450+ scientists & process engineers, the facility has 21 research labs (9 process R&D, 12 discovery chemistry), analytical R&D labs, a process engineering and delivery block capable of handling up to a kilogram level. The site follows phase-appropriate quality systems and is a 21 CFR compliant USFDA site for phase I supplies.
Integrated manufacturing centre
Sai Life Sciences’ flagship manufacturing centre delivering cGMP API and intermediates for several late phase and commercial molecules across US, Europe and Japan. The facility has a capacity of 400 KL with manufacturing blocks designed as multi-purpose production trains for quick turnaround. The site is a zero liquid discharge facility and has undergone successful audits by the USFDA, PMDA Japan and COFEPRIS Mexico, apart from over 600 audits by our innovator pharma & biotech customers.
Discovery Biology lab
An 8,500 square feet lab in Cambridge, Massachusetts focusing on in vitro biology (molecular, cellular and biochemical assays) and exploratory & innovative experiments towards new target identification, target validation, new assay development & validation using targeted genome editing technology (CRISPR-CAS9). The main areas of therapeutic focus are oncology and immuno-oncology. Scheduled to open in August 2019, the Lab will focus on driving innovative discovery programs for start-ups and biotech companies in the region.
Manchester, United Kingdom
Process R&D lab
A process R&D and kilo lab facility in Manchester, UK focusing on complex and niche chemistries. Equipped with 20 fume hoods, analytical R&D, 20-100 litre glass vessels and hydrogenation, the lab will serve to work closely with our customers across UK and EU adding value to their NCE developmental programs. The facility is slated to open in October 2019.
Research & Technology Centre
Slated for launch in May 2020, this new Research & Technology centre adjoining our current R&D facility in Hyderabad will augment our capabilities in providing superior scientific solutions and serve as the nerve-centre for Sai’s integrated discovery and development services to our customers globally. We are adding 12 process R&D labs, 10 medicinal chemistry labs, a tech block equipped with pilot-scale flow reactors, catalyst screening set-up, spray drying and crystallization infrastructure among others.